Whipple's disease: Multiple systemic and neurological relapses

[Whipple's disease: multiple systemic and neurological relapses. Reply].

Whipples disease: a review

Whipple’s disease was described in 1907 and given the name “intestinal lipodystrophy” until it was found that the agent responsible is a bacterium named Tropheryma whipplei. It’s a rare disease which occurs predominantly in males aged 30-60. The small intestinal mucosa is always affected with lesions that are specific to this disease. Replacement of most of cellular elements in the lamina propr...

Systemic sclerosis, transient neurological symptoms, and macrovascular disease.

disorder of unknown etiology, characterized by sclerotic skin and /or multisystem internal organ involvement. Severe secondary Raynaud’s phenomenon due to vasospasm and intimal proliferation in small vessels frequently leads to digital ulceration and ischemia. Internal organ manifestations variably involve the gastrointestinal, renal, cardiac, and pulmonary systems. Neurological symptoms are un...

Cortical relapses in multiple sclerosis.

BACKGROUND Multiple sclerosis (MS) is a white and grey matter disease of the central nervous system (CNS). It is recognized that cortical damage (i.e. focal lesions and atrophy) plays a role in determining the accumulation of physical and cognitive disability that is observed in patients with progressive MS. To date, an association of cortical lesions with clinical relapses has not been describ...

Peripheral neuropathy in Whipples disease: a case report.

Whipples disease is a chronic multisystem inflammatory disease with predominantly gastrointestinal manifestations due to Tropheryma whipplei infection. Typical neurological abnormalities include dementia, eye movement abnormalities, hypothalamic dysfunction and oculomasticatory myorhythmias. The literature on peripheral neuropathy in Whipples disease is sparse and the involvement of peripheral ...